Lineage-specific
Nettet14. feb. 2024 · Dynamic dysregulation of the counteracting lineage-specific transcription factors (TFs), containing adenomatous TFs NKX2-1 and FOXA2, and squamous TFs TP63 and SOX2, finely tuned the lineage transition via … Nettet14. jun. 2024 · Lineage-specific rediploidization is a mechanism to explain time-lags between genome duplication and evolutionary diversification Fiona M. Robertson, Manu Kumar Gundappa, Fabian Grammes, Torgeir R. Hvidsten, Anthony K. Redmond, Sigbjørn Lien, Samuel A. M. Martin, Peter W. H. Holland, Simen R. Sandve & Daniel J. Macqueen
Lineage-specific
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NettetLineage-specific sequence evolution and exon edge conservation partially explain the relationship between evolutionary rate and expression level in A. thaliana. 2015 Jun;24 (12):3093-106. Nettet12. apr. 2024 · IL-6 signaling in allergen-specific T cells is required to suppress Th2 lineage commitment We next determined whether IL-6 signaling in T cells is required for the suppression of Th2 cell responses.
Nettet15. aug. 2016 · A method to account for this regulatory heterogeneity identified cancer-specific deviations and implicated HOX factors as key regulators of preleukemic hematopoietic stem cell characteristics. Nettet2. nov. 2024 · “Lineage-specific genes” are defined operationally as genes that lack detectable homologs in all species outside of a monophyletic group [ 1 ]. Also referred to as “taxonomically-restricted genes” [ 2, 3 ], and as “orphan genes” when found only in a single species [ 4, 5 ], they are ubiquitous in the genomes of sequenced organisms.
Nettet6. jul. 2007 · The lineage-specific dependency concept emphasizes the lineage-specific dependence of cancer cells for their survival and/or proliferation on cellular lineage–governing master regulatory genes and the importance of these genes in shaping the range of cancer-specific genetic and epigenetic alterations in a lineage-specified … Nettet12. apr. 2024 · To probe how lineage-specific CRs sense distinct chemicals, we compared structural features of squid and octopus CRs and assessed how they diverge from ancestral nicotinic receptors.
Nettet1. aug. 2014 · Lineage-specific sdAbs recognised the head domain, whereas, sdAbs identified as cross-reactive could be classified as either head binding or stem binding. Using yeast display, we were able to correlate lineage specificity with naturally occurring sequence divergence, at residue 122 in the highly variable 120 loop of the HA1 domain. how check node js versionNettetThese were chosen over cell type-specific regulons, such as Sox9, Sox 10, and Mecom, on the basis that lineage-specific effects were less likely to be reproducible in the m.5024C>T MEF cells. Knockdown of E2f3 , Taf1 , Maz , and Bclaf1 suppressed MEF cell proliferation, with the greatest impact on high heteroplasmy clones ( Figure 7 D). siRNA … how check my ramNettet19. sep. 2024 · The lineage-specific duplication events of bitter taste receptor genes (Tas2rs) have been identified in a number of vertebrates, but functional evolution of new Tas2r copies after duplication remains largely unknown. how many pieces in jets party trayNettet19. apr. 2004 · To investigate the specificity and stability of lineage-specific gene expression, we included expression patterns of several continuous cell lines including Epstein–Barr virus-transformed lymphoblasts, T and B cell lymphomas, … how check my motherboard modelNettetMutation-specific and cell lineage-specific transcriptional signatures. Pseudobulk analysis also revealed mutation-specific differential expression of mitochondrial genes at the level of the whole embryo ( Figure 4 E) and in pooled cells from specific lineages ( … how check my motherboardNettetOnce the JAKs are activated by the lineage-specific hematopoietic growth factors, a number of secondary signaling molecules are phosphorylated, and these initiate numerous events that promote... how many pieces in mahjongNettet18. mar. 2010 · Our analysis revealed lineage-specific (LS) genomic regions in F. oxysporum that include four entire chromosomes and account for more than one-quarter of the genome. how many pieces in one sushi roll