Impact of mirna in atherosclerosis
Witryna14 lis 2024 · MiR-495 had an effect on endothelial cell proliferation and migration pathways by repressing CCL2 expression (Hartmann et al. 2015) and miR-495 inhibition could decrease accelerated atherosclerosis and increase plaque stability, contributing to the prevention of restenosis (Welten et al. 2024). WitrynaHere, we aimed to screen the atherosclerosis-associated miRNAs and preliminarily investigate the potential regulatory mechanism of... Endothelial Cells, Atherosclerosis and Mesenchymal Cells ...
Impact of mirna in atherosclerosis
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WitrynaCorrigendum to: “Krüppel-like factor 14 inhibits atherosclerosis via mir-27a-mediated down-regulation of lipoprotein lipase expression in vivo” [Atherosclerosis Volume … WitrynaNational Center for Biotechnology Information
Witryna13 gru 2024 · Circulating MiRNAs as Potential Clinical Biomarkers for Atherosclerosis and CVD. Extensive research has revealed that miRNAs are extremely stable and … WitrynaMaintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and vascular inflammation. Endothelial dysfunction is encompassed …
WitrynaInhibition of miR-33 results in increased cholesterol efflux and HDL-cholesterol levels in mice. In this study we examined the effect of miR-33 inhibition in a mouse model of atherosclerosis and observed significant reduction in atherosclerotic plaque size. At the end of the study, gene expression in macrophages from the atherosclerotic plaques … WitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a role in endothelial function and atherosclerosis. Choline, betaine, and L-carnitine, found in animal foods, are metabolized into trimethylamine (TMA) by the gut …
Witryna27 lip 2024 · These findings imply that miR-142-5p may plays a role in the development of atherosclerosis. Next, we tested the effect of miR-142-5p on the 3′-UTR of ABCA1 using luciferase reporter constructs and demonstrated that miR-142-5p dose-dependently reduced mouse and human ABCA1 3′-UTR activities (Figure S11A and …
Witryna3 sty 2024 · Introduction: Atherosclerosis is a chronic disease characterized by the inflammatory process and lipid depositions. We previously reported that microRNA-216a (miR-216a) can accelerate the progression of atherosclerosis by promoting the polarization of M1 pro-inflammatory phenotype. Ginsenoside Rb2 (Rb2), the major … rc theater moviesWitryna17 gru 2024 · This study presents novel evidence linking miR-155 biology with the progression and regression of atherosclerosis. Herein, we have shown an inverse … rc theater lexingtonWitrynaMiRNA controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ, and plays the roles in endothelial cell (EC), vascular smooth … sims wssc.vic.edu.auWitryna22 lip 2024 · The authors hypothesized that ACP5, as a direct target of lncRNA-H19, causes atherosclerosis by affecting cellular proliferation and apoptosis (Huang et al. 2024). Many studies have reported that lncRNA-H19 functions as a ceRNA to sponge its target miRNAs such as microRNA let-7 (Hsu et al. 2014; Sun et al. 2024b; Cao et al. … sims yit female body preset 3Witryna22 sie 2024 · Impact of miRNA in Atherosclerosis. miRNAs have received most of the attention during the last decades in particular for their role in tempering gene … simsy clineWitryna24 mar 2024 · Atherosclerosis (AS) is a chronic arterial disorder and a significant determinant of vascular death [].Fatty streaks in arterial walls regularly develop into characteristic plaques and atheroma [].The acute rupture of these atheromatous plaques leads to local thrombosis, causing partial or total occlusion of the affected artery [].AS … sims yala jowl right sliderWitryna29 lis 2024 · MiR-155 is an important microRNA that modulates inflammation in atherosclerosis, but the role of miR-155 in the regulation of the NLRP3 inflammasome is still unknown. ... Corbalan-Campos J, et al. Regulation of Csf1r and Bcl6 in macrophages mediates the stage-specific effects of microRNA-155 on … sims y2k outfits