Dysphagia optimised imrt

Author: kayj

August undefined, 2024

WebJul 1, 2024 · Increasingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden … WebFeb 24, 2024 · The preferential sparing achievable with intensity-modulated radiotherapy (IMRT) of key swallowing structures implicated in post-radiation dysfunction, such as the pharyngeal constrictor muscles (PCM), has generated significant research into toxicity-mitigating strategies. The lack of randomised evidence, however, means that there …

Dysphagia and aspiration after chemoradiotherapy for head-and …

WebNov 1, 2015 · In this review, we discuss the swallowing structures responsible for functional impairment, analyse the studies that have explored the dose–response relationship between these critical structures and late dysphagia, and consider the merits of reported dysphagia-optimised IMRT (Do-IMRT) approaches, thus far. WebOct 26, 2024 · This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. … chromosome before interphase

Quality assurance of dysphagia-optimised intensity …

WebJun 8, 2024 · DO-IMRT, which has been pioneered by researchers from The Royal Marsden Hospital and The Institute of Cancer Research, London, is optimised to reduce the risk of swallowing difficulties, known as dysphagia. It does this by reducing radiation to the pharyngeal muscles, which support swallowing. WebOct 6, 2016 · The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised … Webingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden outcomes for pharyngeal … chromosome before and after dna replication

DARS: a phase III randomised multicentre study of dysphagia

A comparison of swallowing dysfunction after three-dimensional ...

WebJun 8, 2024 · DO-IMRT, which has been pioneered by researchers from The Royal Marsden Hospital and The Institute of Cancer Research, London, is optimised to reduce the risk … WebThe results of the DARS study by Nutting et al. clarified the advantage of limiting the mean doses to key swallowing structures like the pharyngeal constrictors with a significant reduction in patient reported swallowing difficulties … chromosome before s phase chromosome behavior

"WebJun 14, 2024 · Purpose Dysphagia is one of the most important treatment-related side effects in head and neck cancer (HNC), as it can lead to severe life-threating complications such as aspiration pneumonia and malnutrition. Intensity-modulated radiotherapy (IMRT) could reduce swallowing dysfunction by producing a concave dose distribution and … " - Dysphagia optimised imrt

Dysphagia optimised imrt

Dysphagia and aspiration after chemoradiotherapy for head-and …

WebJul 15, 2024 · Dysphagia-Optimized IMRT Shows Significance in Head and Neck Cancer. Christopher Nutting, MD, discusses the results of a randomized phase 3 trial … WebFeb 11, 2024 · Recent evidence suggests that reducing radiotherapy dose delivered to specific anatomical swallowing structures [Swallowing Organs at Risk (SWOARs)] may improve swallowing outcomes post-treatment for patients with head and neck cancer. However, for those patients with tumours of the oropharynx, which typically directly …

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WebLevels of a dysphagia diet. The International Dysphagia Diet Standardisation Initiative (IDDSI) has created a diet plan or framework for people with dysphagia. The dysphagia … WebThe results of the DARS study by Nutting et al. clarified the advantage of limiting the mean doses to key swallowing structures like the pharyngeal constrictors with a significant …

Webingly, there is a focus to establish dysphagia-optimised IMRT (Do-IMRT) strategies [18], which could translate into improved long-term symptom burden outcomes for pharyngeal cancer patients by reducing dose to critical swallowing structures. Reﬁnements to existing technology, in the form of arc-based IMRT and adaptive radiotherapy, WebIMRT had a statistically significant advantage over 3D CRT, in terms of V30 (p=0.051), V50 (p=0.002), V60 (p=0.002), and D80 (p=0.023) for the swallowing structures taken together. ... Further prospective studies are required to confirm these findings. Dysphagia-optimised IMRT is needed to improve swallowing status and quality of life in these ...

WebJun 1, 2024 · A new optimised intensity-modulated radiation therapy (IMRT) pioneered at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, has been shown to spare head and neck cancer patients’ adverse life-long side effects post treatment. The initial results from the Dysphagia-Aspiration Related Structures (DARS) … WebDec 1, 2024 · Dysphagia-optimised IMRT resulted in a significantly higher mean MDADI score at 12 months post-radiotherapy (78 versus 70; P = 0.02) with no apparent detriment to local control [21, 22]. Studies such as PARSPORT and DARS constitute a structured, evidence-based approach to the introduction of new radiotherapy technology and …

WebFeb 24, 2024 · The preferential sparing achievable with intensity-modulated radiotherapy (IMRT) of key swallowing structures implicated in post-radiation dysfunction, such as the …

WebMar 18, 2024 · Petkar I, Rooney K, Roe JWG, et al. DARs: a phase III randomised multicentre study of dysphagia-optimised intensity modulated radiotherapy (do-IMRT) versus standard intensity-modulated radiotherapy (S-IMRT) in head and neck cancer. BMC Cancer. 2016;16:1–10. Article Google Scholar chromosome before replicationWebDec 1, 2004 · Purpose To identify the anatomic structures whose damage or malfunction cause late dysphagia and aspiration after intensive chemotherapy and radiotherapy (RT) for head-and-neck cancer, and to explore whether they can be spared by intensity-modulated RT (IMRT) without compromising target RT. chromosome being unfirled cartoony imageWebThe following are examples of nursing diagnoses that could be used when caring for a patient with dysphagia: impaired swallowing. risk for aspiration. diarrhea related to … chromosome behaviour during meiosisWebMay 20, 2024 · A multi-centre randomised phase 3 trial investigated dysphagia-optimised IMRT (DO-IMRT) to spare DARS for 112 patients with oropharyngeal and … chromosome binWebOct 6, 2016 · The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised … chromosome bilderWebThis study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for head and neck cancer patients, and the potential impacts on swallowing function. This study examined knowledge and practices of speech pathologists (SPs) and radiation therapists (RTs) regarding plan optimisation for … chromosome behavior in mitosisWebsparing strategies. The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised intensity- modulated radiotherapy (Do-IMRT) will lead to an improvement in long- term swallowing function without having any detrimental impact on disease- chromosome behaviour in mitosis